Steve Carell

Gru (voice)

Kristen Wiig

Lucy (voice)

Benjamin Bratt

Eduardo/El Macho (voice)

Miranda Cosgrove

Margo (voice)

Russell Brand

Dr. Nefario (voice)

Ken Jeong

Floyd (voice)

Steve Coogan

Silas (voice)

Elsie Fisher

Agnes (voice)

Dana Gaier

Edith (voice)

Moisés Arias

Antonio (voice)