Casey Kasem

Shaggy Rogers (voice)

Frank Welker

Scooby-Doo / Fred Jones / Wiki-Tiki / Interviewer (voice)

Mindy Cohn

Velma Dinkley (voice)

Grey DeLisle

Daphne Blake / Auntie Mahina / Local Woman #2 (voice)

Ray Bumatai

Little Jim (voice)

Tia Carrere

Snookie / Local Woman #1 (voice)

Teri Garr

Mayor Molly Quinn (voice)

Mario López

Manu Tuiama / Mainland Surfer (voice)

Adam West

Jared Moon (voice)

Don Ho

Special Musical Guest (voice)